Neurosyphilis Bibliographic review

Main Article Content

Ricardo Murillo-Varela

Abstract

The syphillis is a pathology that affects the humanity from more than 500 years, in his origins they mixed the typical manifestations of the disease with the clinic presentattion from other diseases from that time, consider as a punishment sent by the gods of every civilization affected. His investigation has been stepped in the last 130 years, from the discovery, the clínical presentation, phases, etiology, the diagnostic and therapeutic methods were developed, wich evolved from the application of mercury to the correct and justified use of antibiotics. In the past was called ²the great imitator² due to his capacity to simulate other diseases. In the present day it is a disease that affects worldwide, it has been registered a few small outbreaks, nevertheless, still be a long way to consider that we have improves in his morbility, because is related to the sexual behavior of the people. Between the general population there is some groups with a much higher incidence than the rest, the men that have sex with men, almost the 63% of the all cases are described in this group. Another population that is important are the patients with a previous infection with adquired immunodeficiency syndrome or AIDS, such people the diagnose is really difficult to be make, because the syphillis simulates other pathologies and they have a faster progression than in other patients. It is vital to indicate that the Neurosyphillis can be presented in any phase of the condition, the neurological affectation depends on multiple condition of the host and his respond to treatment. There is no current recommendations to the treatment of the psychiatric manifestations of the Neurosyphillis, it is a very rare condition, there is no guidelines so i will show how it is treated in other latitudes, to extrapolate what is usefull to the psysician in case he or she have to face a patient carring this disease.

Downloads

Download data is not yet available.

Article Details

How to Cite
Murillo-VarelaR. (2019). Neurosyphilis. Acta Académica, 54(Mayo), 223-246. Retrieved from http://201.196.25.14/index.php/actas/article/view/106
Section
Acta Médica

References

Angermüller, M. (2009). Neurosífilis: Caso clínico y revisión bibliográfica. Revista Médica de Costa Rica y Centroamérica. LXVI (587): 95-103.
Aziz, T. & Holman, R. (2010) The Argyll-Robertson pupil. American Journal of Medicine. 123 (2), 120-121.
Berdasquera C., D., Lazo Á., M., Galindo S., B. & Gala G., A. (2004) Sífilis: pasado y presente. Revista Cubana de Higiene y Epidemiología, 42(2).
Centers for Disease Control and Prevention. (2012?) Syphilis - CDC Fact Sheet. Recuperado de http://www.cdc.gov/std/ syphilis/STDFact-Syphilis.htm
Chahine, L., Khoriaty, R., Tomford, W. & Hussain, M. (2011) The changing face of neurosyphilis. International Journal of Stroke, 6 (2), 136-143.
Danoso, A., Urzúa, R., Slachevsky, A. & Silva, C. (2012). Parálisis General Sifilítica: Presentación de 5 Casos. Revista Médica de Chile. 140 (5): 625-628.
García, P., Grassi, B., Fich, F. Salvo, A. & Araya, L. (2011) Diagnóstico de la infección por Treponema pallidum en pacientes con sífilis temprana y neurosífilis mediante reacción en cadena de polimerasa. Revista Chilena de Infectología, 28 (4) 310-315.
Ghanem, K. (2010). Neurosyphilis: A Historical Perspective and Review. CNS Neuroscience and Therapeutics. 16 (5), 157-168.
Jalón M., A., San Martín Blanco, A., García R., J., Martín Benito J. , Rodríguez F., O., González A., R., Alvarez M., M., Rodríguez R. L. & Regadera S., F. (2006). Neurosífilis y disfunción vesical. Archivos Españoles de Urología. 59 (2), 189-192.
Jiménez, J., Ladino, L., Uribe, C., Guerra, A., Ciro, J., Hernández, O. & Ochoa, J. (2012) Neurosífilis meningovascular con trombosis de la arteria basilar. Biomédica. 32 (1), 7-12.
LaFond, R., Luckehart, S. (2006) Biological basis of syphilis. Clinical Microbiology Reviews. 19 (1), 29-49.
Longo, D., Fauci, A., Kasper, D., Hauser, S., Jameson, J. & Loscalzo, J. (2012) Harrison: principios de medicina interna. (18a ed.). México: McGraw-Hill.
Marra, C., Tantalo, L., Maxwell, C., Ho, E., Sahi, S. & Jones, T. (2012) The rapid plasma reagin test cannot replace the venereal disease research laboratory test for neurosyphilis diagnosis. Sex Trans Dis. 39 (6), 453-457
Marra, C., Tantalo, L., Maxwell, C., Sahi, S. & Lukehart, S. (2010) CXCL13 as a cerebrospinal fluid marker for neurosyphilis in HIV-infected patients with syphilis. Sex Trans Dis. 37 (5), 283287.
Mattei, P., Beacjkofsky, T., Gilson, R. & Wisco, O. (2012) Shypilis:
a reemerging infection. American Family Physician, 86 (5): 433440.
Pandey, S. (2011) Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis. Journal Spinal Cord Medicine, 34(6), 609-611.
Pless, M., Kroshinsky, D., LaRocque, R., Buchbinder, B. & Duncan, L. (2010). Case records of the Massachusetts General Hospital. Case 26-2010. A 54-year-old man with loss of vision and a rash. The New England Journal of Medicine. 363 (9), 865-874.
Robertson, A. (1869). On an interesting series of eye symptons in a case of spinal disease with a remark on the action of the belladone on the iris. Edinburg Medical Journal, 14, 696-708.
Rosen, T., Vandergriff, T. & Harting, M. (2009) Antibiotic use in sexually transmissible diseases. Dermatologic Clinics, 27 (1), 49-61.
Tucker, J. & Cohen, M. (2011) China’s syphilis epidemic: epidemiology, proximate determinants of spread, and control response. PMC, 587, 136-143.
Viens, N., Watters, T., Vinson, E. & Brigman, B. (2010). Neuropathic artropathyof the hip as a sequela of undiagnosed tertiary syphilis. Clinical Orthopaedics and Related Research, 468 (11), 3126-3131.
Zhou, P., Li, K., Lu, H., Qian, Y., Gu, X., Gong, W., Tucker, J. & Cohen, M. (2010) Azythromycin treatment failure among primary and secondary syphilis patients in Shanghai. Sex Trans Dis. 37 (11) 726-729.